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GraviditetEn stor mengde data fra gravide indikerer hverken misdannelser eller toksisitet av paracetamol hos foster/nyfødt barn. Epidemiologiske studier på nevronal utvikling hos barn eksponert for paracetamol in utero viser ikke entydige resultater. Ved langvarig behandling med kodein hos mor under graviditet er det sett neonatal abstinens. Det er sett neonatal respirasjonsdepresjon ved bruk av kodein ved fileødsler. Paralgin forte/Paralgin main skal bare brukes below graviditet hvis fordel oppveier mulig risiko, og da med lavest mulig effektiv dose i kortest mulig tid og lavest mulig frekvens.
En ny studie viser at det smertestillende legemidlet ibux ikke har noen særlig virkning på ryggsmerter. For et par år siden konkluderte Den Norske Legeforening med at heller ikke paracetamol hjelper mot vond rygg.
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Distribusjonsvolumet vil være ca. 5 liter hos et voksent menneske for et legemiddel som hovedsakelig befinner seg i plasma.
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On account of its small possibility of triggering allergic reactions, this drug may be administered in sufferers that are intolerant to salicylates and people with allergic tendencies, including bronchial asthmatics. Particular dosing suggestions must be adopted when administering acetaminophen to little ones.
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Kontakt lege eller apotek dersom du opplever bivirkninger inkludert mulige bivirkninger som ikke er nevnt i dette pakningsvedlegget. Se avsnitt 4.
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Larger rectal doses or an elevated frequency of administration could possibly be utilized to achieve blood concentrations of acetaminophen similar to All those attained following oral acetaminophen administration. Absorption